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Catalase - Links

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[ Catalase Links | Medical Research | for Schools & Colleges ]

Catalase Links:

Catalases: Excellent page on Catalases from the PROMISE database (PROMISE is a wide ranging collection of web-based information about different classes of proteins. It is maintained by Kirill Degtyarenko).
Haem peroxidases: Information on Peroxidases, including Catalase Peroxidases, also from the PROMISE database.
Paula Burch's PhD Thesis: Concise and informative web pages looking at which 'Active Oxygen' species cause cell damage. Excellent section on Catalase. Contains references to many scientific papers.
Peter Nicholls Abstracts: Page listing this researcher's papers on his work on the mechanisms of action of Catalase and of Cytochrome C.
Vienna Biocenter
Catalase: Koller's research group working on Catalase in Vienna. Discusses relationship between catalases and peroxidases, the role of NADPH, the structure of catalase and gives a list of publications on catalase by that group. This page is likely to be updated in the near future with additional publications.
Two Barley Catalase Genes Respond Differentially To Light
The circadian clock gates the light-responsiveness of the CAT2 catalase gene in etiolated Arabidopsis seedlings.: Two interesting articles on the regulation of different catalase genes in plants and the effects of changing light levels on expression of the gene.
X Tertiary Structure of Catalase: For frame enabled browsers this site used to provide a clickable model of Catalase to view.
Molecular Evolution of Catalase Genes: Changes in the Exon/Intron structure of the Catalase gene in plants, used to create a phylogenetic tree of gene relatedness.
Catalase structural alignment: Sequence alignment based on structure of three catalase genes.
X Gene Database: Catalases: Accession number: PF00199
Manganese Catalase: As well as haem containing Catalases there is another class of the enzyme, unrelated at the sequence level, but with similar function. This page shows a proposed mechanism of action of the Manganese Catalases.

Catalase and Medical Research:

Emily's vitiligo: Vitiligo is a skin condition characterised by whitening of the skin especially on exposure to sunlight. It is believed that higher than normal levels of hydrogen peroxide lead to cell death in melanin containing cells in the skin. This page includes a discussion of a dietary approach to treatment of vitiligo.
PAG-VII Association of Catalase gene markers to facial eczema disease resistance in sheep: This abstract shows that there is an association between a defective catalase gene and a particular form of photo sensitive eczema. An unusual connection is that in this case the cause of the eczema is known. It is caused by damage to the liver caused by spores of Pithomyces chartarum.
Relationship Between TNF and Catalase during Oxidative Stress
Superoxide dismutase and catalase in protection of cardiopulmonary: bypass-induced cardiac dysfunction and cellular injury. - Canadian Journal of Cardiology 1996. A study indicating that Oxidative Stress after bypass operations and hence cardiac damage may be reduced by use of catalase and SOD in combination.
Superoxide dismutase, catalase and nitrogenase activity: Physiologia Plantarum published by Munksgaard International
Expression of glutathione peroxidase and catalase in copper-deficient rat liver: Journal of Nutrition (government publications)
Glutathione Peroxidase and Catalase in Liver, Kidney, Testis and Brain Regions of rats following Cadmium exposure: Industrial Health 1989

For Schools & Colleges:

The Effect Of Substrate Concentration On The Activity Of The Enzyme Catalase: How does the activity of Catalase vary with concentration?
Mark Radcliffe's A Level project. (Read the warning).
Ask a Scientist - Reaction of the enzyme catalase with hydrogen peroxide: How does the activity of Catalase vary with temperature?
Hemoprotein Examples: What other proteins have the heme group in them?
part of the www.madsci.org Archives: How come Catalase (and other enzymes) are affected by pH?
www.madsci.org run an internet Question and Answers session with volunteer scientists. Other archive articles on that site (which can be searched by keyword) deal with some other questions which have been asked about catalase.
Worthington Biochem: What is the optimal pH for Catalase?
This page is produced by a supplier of catalase to the scientific and educational communities. It gives a graph of how the efficiency of enzymes vary with pH, including a table of optimal pH's. This table gives pH 7.0 as the optimum for catalase.
Catalase Experiment with Potato: Experimental details for an experiment measuring catalase activity in potato.
University of Kent course BI301: Course on chemical kinetics. Excellent material.

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"Catalase - Links" page last updated 5-July-2003