SeqQuests - A New Bioinfomratics Toolkit

Top Features

SeqQuests is a new collection of bioinformatics software. It is at an early stage.

  • Optimised for Apple silicon: A fast Smith-Waterman amino acid sequence comparison.
  • Dual architecture: Scriptable command-line utilities (python) with optional web-browser/API-endpoint interfaces
  • ~20 twilight zone findings: These suggest database annotation updates.

About SeqQuests

Building open bioinformatics software - using composable pieces.

Code is on GitHub.

GitHub

SeqQuests

Smith Waterman

Running for 36 hours the flagship module of SeqQuests performed an all-on-all Smith-Waterman comparison of UniProt Swiss-Prot (~570,000 sequences) finding many relationships between proteins in the process

Findings →

Additional Tools

The software library additionally includes work on:

  • Displaying sequence composition bias
  • Browsing Swiss-Prot feature tables with a domain viewer
  • Navigating a tree of protein similarities
  • Kabsch 3D alignment